The APEC project addresses the impact of health crises on global tourism by focusing on preparedness, resilience, and long-term viability of destinations within the APEC economies. Unlike past crises, health crises, exemplified by the Covid-19 pandemic, transcend borders, affecting both health and the economy. The project's objectives include enhancing stakeholder capacity through a workshop and case studies, aiding in crisis management, and promoting sustainable tourism development. Key activities encompass virtual discussions, case studies in six APEC economies, a hybrid workshop, and the publication of a handbook. These efforts emphasize a systematic approach to managing health crises, delineating organizational structures, policies, and procedures. Additionally, cross-economy comparisons aim to categorize health crisis phenomena into typical and atypical instances at micro and macro-organizational levels.